Matthew P Frosch Selected Research

Cerebral Amyloid Angiopathy (Congophilic Angiopathy)

1/2022	Histopathological correlates of haemorrhagic lesions on ex vivo magnetic resonance imaging in immunized Alzheimer's disease cases.
1/2022	Perivascular space dilation is associated with vascular amyloid-β accumulation in the overlying cortex.
1/2022	The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.
1/2020	Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain.
12/2019	Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0.
11/2019	Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue.
1/2019	Different microvascular alterations underlie microbleeds and microinfarcts.
7/2017	Emerging concepts in sporadic cerebral amyloid angiopathy.
1/2017	Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy.
11/2015	Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy.

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Matthew P Frosch Research Topics

Disease

76	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2002
25	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 01/2022 - 02/2004
19	Amyloid Plaque 01/2021 - 02/2002
15	Dementia (Dementias) 01/2022 - 05/2002
11	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 11/2019 - 11/2007
9	Parkinson Disease (Parkinson's Disease) 01/2022 - 05/2002
9	Tauopathies 12/2021 - 10/2011
9	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021 - 02/2003
8	Hemorrhage 12/2020 - 11/2008
7	Frontotemporal Dementia (Semantic Dementia) 03/2014 - 10/2006
6	Cognitive Dysfunction 01/2022 - 01/2012
6	Corticobasal Degeneration 12/2021 - 11/2007
6	Neoplasms (Cancer) 01/2021 - 02/2010
6	Gliosis 01/2018 - 08/2007
5	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 02/2010
5	Glioma (Gliomas) 01/2021 - 01/2013
5	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 11/2019 - 11/2007
5	Inflammation (Inflammations) 01/2019 - 02/2004
4	Cerebral Hemorrhage 04/2020 - 11/2012
4	Hemorrhagic Stroke 11/2015 - 07/2005
3	Synucleinopathies 01/2022 - 10/2017
3	Pick Disease of the Brain (Pick's Disease) 01/2020 - 01/2008
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2020 - 01/2008
3	Multiple System Atrophy 01/2019 - 11/2015
3	Brain Neoplasms (Brain Tumor) 11/2017 - 02/2012
3	Huntington Disease (Huntington's Disease) 11/2017 - 05/2010
3	Lewy Body Disease (Lewy Body Dementia) 01/2013 - 01/2012
2	Neuroinflammatory Diseases 01/2022 - 11/2015
2	Atrophy 12/2021 - 01/2008
2	Infections 01/2021 - 08/2011
2	Siderosis 12/2020 - 07/2011
2	Familial Cerebral Amyloid Angiopathy 04/2020 - 11/2008
2	Myoclonus (Nocturnal Myoclonus) 01/2019 - 01/2016
2	Amyloidosis 01/2019 - 09/2008
2	Drug Resistant Epilepsy 01/2016 - 01/2009
2	Adrenoleukodystrophy (Adrenoleukodystrophy, X-Linked) 11/2015 - 06/2008
2	Demyelinating Diseases (Demyelinating Disease) 11/2015 - 06/2008
2	Disease Progression 04/2013 - 01/2013
2	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2012 - 08/2011
2	Cerebrovascular Trauma 01/2012 - 01/2012
2	Hippocampal Sclerosis 01/2012 - 01/2012
2	Stroke (Strokes) 12/2011 - 06/2010
2	Infarction (Infarctions) 08/2011 - 02/2010
2	Nervous System Diseases (Neurological Disorders) 05/2010 - 11/2005
2	Tuberous Sclerosis (Bourneville's Disease) 12/2009 - 01/2009
1	Cerebral Small Vessel Diseases 01/2022
1	Melanoma (Melanoma, Malignant) 01/2022

Drug/Important Bio-Agent (IBA)

51	Amyloid (Amyloid Fibrils)IBA 01/2022 - 02/2002
23	Amyloid beta-PeptidesIBA 01/2021 - 01/2002
21	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2003
10	Peptides (Polypeptides)IBA 01/2022 - 12/2003
8	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2016
8	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2019 - 01/2008
6	SynucleinsIBA 01/2022 - 11/2015
6	Biomarkers (Surrogate Marker)IBA 12/2019 - 04/2013
6	ProgranulinsIBA 05/2014 - 01/2009
4	tau Proteins (tau Protein)IBA 10/2021 - 11/2007
4	Apolipoproteins E (ApoE)IBA 01/2020 - 10/2012
4	AntibodiesIBA 01/2019 - 05/2002
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 11/2017
3	Presenilin-1IBA 12/2021 - 03/2005
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021 - 01/2017
3	LipidsIBA 09/2019 - 10/2017
3	Protein Isoforms (Isoforms)IBA 11/2018 - 10/2006
3	Fatty Acids (Saturated Fatty Acids)IBA 11/2015 - 02/2003
3	UbiquitinIBA 10/2012 - 01/2008
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 08/2012 - 01/2009
3	Messenger RNA (mRNA)IBA 11/2007 - 05/2006
3	alpha-SynucleinIBA 12/2005 - 05/2002
2	IronIBA 01/2022 - 12/2020
2	AN-1792IBA 01/2022 - 05/2010
2	Carrier Proteins (Binding Protein)IBA 12/2021 - 01/2019
2	formic acid (formate)IBA 10/2021 - 05/2006
2	FibrinIBA 01/2021 - 01/2019
2	Superoxide Dismutase-1IBA 01/2020 - 11/2010
2	Apolipoprotein E4IBA 01/2020 - 07/2012
2	7- (6- fluoropyridin- 3- yl)- 5H- pyrido(4,3- b)indoleIBA 10/2019 - 01/2017
2	CytokinesIBA 01/2019 - 11/2015
2	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2017 - 03/2013
2	Matrix Metalloproteinases (MMPs)IBA 11/2015 - 06/2009
2	ApolipoproteinsIBA 09/2014 - 07/2012
2	polyglutamineIBA 04/2013 - 05/2010
2	Coloring Agents (Dyes)IBA 01/2013 - 02/2012
2	thioflavin TIBA 08/2012 - 08/2010
2	PresenilinsIBA 01/2010 - 03/2005
2	Flavin-Adenine Dinucleotide (FAD)IBA 01/2010 - 03/2005
2	trans-sodium crocetinate (crocetin)IBA 12/2009 - 01/2009
2	Insulysin (Insulin-Degrading Enzyme)IBA 12/2003 - 04/2003
1	CalciumIBA 01/2022
1	Aspartic Acid (Aspartate)FDA Link 01/2022
1	Type 1 Melanocortin ReceptorIBA 01/2022
1	Waste Products (Waste Product)IBA 01/2022
1	NucleotidesIBA 01/2022
1	PrionsIBA 10/2021
1	sarkosylIBA 10/2021
1	Glycogen Synthase (Synthase I)IBA 02/2021
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2021

Therapy/Procedure

7	Therapeutics 01/2022 - 09/2002
3	Immunotherapy 01/2022 - 02/2007
2	Drug Therapy (Chemotherapy) 11/2016 - 05/2016